LPRE

LPRE
Laboratory of Polymer Reaction Engineering

LPRELaboratory of Polymer Reaction Engineering

Mission

The Laboratory of Polymer Reaction Engineering (LPRE) was established in 1985. The Lab’s mission is to carry out fundamental and applied research in advanced computational methods, functional materials, green chemistry, health, energy and environment with special emphasis on dynamic simulation of chemical, biochemical and biological process systems, digital manufacturing , functional materials, biopolymers, biofuels, high added-value biochemicals, controlled drug delivery systems and biomedical engineering applications. The LPRE is financially supported through research funds received from the Greek Secretariat of Research and Technology, the European Union, and major international polymer manufacturing industries.

Research focus

Presently, the research activities of the Lab are focused on the following areas:

  1. Advanced computational methods and digital materials manufacturing;
  2. Functional materials for analytical separations and water purification;
  3. Microbial production of biopolymers and biochemical ; 
  4. Development of novel controlled drug delivery formulations and vaccines.

Main scientific directions

  1. Digital Production
    Present efforts of LPRE aim at the development of powerful, modular, and predictive design and software tools for dynamic simulation of chemical and biochemical processes. In particular, current research efforts are focused on

    1. mechanistic modeling, simulation and optimization of polymerization, biochemical and biological systems;

    2. data-based modeling and process monitoring, development of molecular structure – end-use property relationships by machine-learning approaches.

  2. Functional Materials

    1. Synthesis of hydrogels for biomedical applications;

    2. Synthesis and application of organic-inorganic hybrid materials in coatings;

    3. Synthesis of functional materials by molecular imprinting for analytical separations and sensor applications;

    4. Membrane assisted capacitive deionization by carbon based materials and highly conductive polymers for water desalination;

    5. Sustainable production of nanocellulose for the development of high performance nanoscale materials.

  3. Microbial Production

    1. Bioconversion of biomass and wastes/residues to biopolymers, biofuels and high-added value biochemicals via microbial bioprocesses; 

    2. Enzymatic biocatalysis and cell factories (bacterial, yeast and microalgal) for biochemicals production;

    3. Biomaterials production through 2nd (from lignocellulosic biomass) and 3rd (via microalgal cultures) generation of biorefineries.

  4. Biomedical Engineering

    1. Synthesis of biodegradable/biocompatible polymer and lipid based nanoparticles, nanovesicles, nanoemulsions for mucosal delivery of therapeutic biomolecules and antigens;

    2. Development of multifunctional biomimetic hydrogels;

    3. Development of nanocarrier based novel vaccine formulations;

    4. The digital physiological human (i.e., simulation of nasal and pulmonary particle deposition, nasal/pulmonary drug delivery systems).

Projects & Activities

LPRE

FUELGAE

GA 101122151 

LPRE

Hiperion

/MIS 5131353/Τ2ΕΔΚ-01394 

LPRE

Bio2Brain

/GA 956977 

LPRE

NanoVacLeish

/MIS 5031816/Τ1ΕΔΚ-03902 

LPRE

CO2 BioProducts

/MIS 5031682/Τ1ΕΔΚ-02681 

LPRE

NANOPOL

/MIS 5031218/Τ1ΕΔΚ-02663 

Personnel

LPRE

Akylas Victoras

Scientific Personnel
, Chemical Engineer
LPRE

Alexopoulos Alexandros

Researcher
, Principal Researcher
, Chemical Engineer, PhD
LPRE

Bakola Veroniki

PhD Candidate
, Chemical Engineer, MSc
LPRE

Baltsas Apostolos

Scientific Personnel
, Chemical Engineer
LPRE

Bloutsou Maria

Administrative & Technical Staff
, Chemical Engineer
LPRE

Kammona Olga

Member of SC, Researcher
, Principal Researcher
, Chemical Engineer, PhD
LPRE

Kiparissides Costas

Researcher Emeritus
, Professor Emeritus
LPRE

Kotrotsiou Olympia

Collaborating Researcher PhD
, Chemical Engineer, PhD
LPRE

Pavlou Alexandros

Collaborating Researcher PhD
, Chemical Engineer, PhD
LPRE

Penloglou Ioannis

Collaborating Researcher PhD
, Chemical Engineer, PhD
LPRE

Pladis Prokopios

Researcher
, Principal Researcher
, Chemical Engineer, PhD
LPRE

Platidou Aleka

Administrative & Technical Staff
, Petroleum Technologist
LPRE

Tsanaktsidou Jenny

PhD Candidate
, Chemical Engineer, MSc

Publications

Kiparissides C.

On the Elucidation of Polymer Fouling Mechanisms and Ethylene Decomposition in High-Pressure LDPE Tubular Reactors

2022

Macromolecular Reaction Engineering, 2200023, 2022

Kiparissides C., Pladis P.

On the prediction of suspension viscosity, grain morphology, and agitation power in SPVC reactors

2022

The Canadian Journal of Chemical Engineering, 100 (4), 714-730, 2022

Tsanaktsidou E., Kammona O., Kiparissides C.

Recent Developments in Hyaluronic Acid-Based Hydrogels for Cartilage Tissue Engineering Applications

2022

Polymers 14 (4), 839, 2022

Kiparissides C., Pladis P.

On the Prediction of Suspension Viscosity, Grain Morphology, and Agitation Power in SPVC Reactors

2021

The Canadian Journal of Chemical Engineering (SI)

Karageorgos F., Kiparissides C.

Prediction of Viscoelastic Properties of Enzymatically Crosslinkable Tyramine–Modified Hyaluronic Acid Solutions Using a Dynamic Monte Carlo Kinetic Approach

2021

International Journal of Molecular Sciences, 22(14), 7317

Kammona O., Tsanaktsidou E.

Nanotechnology-Aided Diagnosis, Treatment and Prevention of Leishmaniasis

2021

International Journal of Pharmaceutics, 605, 120761

Kiparissides C., Vasileiadou A., Karageorgos F., Serpetsi S.

A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics

2020

Industrial & Engineering Chemistry Research, 59(6), 2548-2565

Tsanaktsidou E., Kammona O., Labude N., Neuss S., Krüger M., Kock L., Kiparissides C.

Biomimetic Cell-Laden MeHA Hydrogels for the Regeneration of Cartilage Tissue

2020

Polymers, 12 (7), 1598

Kiparissides C.

On the Elucidation of Polymer Fouling Mechanisms and Ethylene Decomposition in High-Pressure LDPE Tubular Reactors

2022

Macromolecular Reaction Engineering, 2200023, 2022

Kiparissides C., Pladis P.

On the prediction of suspension viscosity, grain morphology, and agitation power in SPVC reactors

2022

The Canadian Journal of Chemical Engineering, 100 (4), 714-730, 2022

Tsanaktsidou E., Kammona O., Kiparissides C.

Recent Developments in Hyaluronic Acid-Based Hydrogels for Cartilage Tissue Engineering Applications

2022

Polymers 14 (4), 839, 2022

Kiparissides C., Pladis P.

On the Prediction of Suspension Viscosity, Grain Morphology, and Agitation Power in SPVC Reactors

2021

The Canadian Journal of Chemical Engineering (SI)

Karageorgos F., Kiparissides C.

Prediction of Viscoelastic Properties of Enzymatically Crosslinkable Tyramine–Modified Hyaluronic Acid Solutions Using a Dynamic Monte Carlo Kinetic Approach

2021

International Journal of Molecular Sciences, 22(14), 7317

Kammona O., Tsanaktsidou E.

Nanotechnology-Aided Diagnosis, Treatment and Prevention of Leishmaniasis

2021

International Journal of Pharmaceutics, 605, 120761

Kiparissides C., Vasileiadou A., Karageorgos F., Serpetsi S.

A Computational Systems Approach to Rational Design of Nose-to-Brain Delivery of Biopharmaceutics

2020

Industrial & Engineering Chemistry Research, 59(6), 2548-2565

Tsanaktsidou E., Kammona O., Labude N., Neuss S., Krüger M., Kock L., Kiparissides C.

Biomimetic Cell-Laden MeHA Hydrogels for the Regeneration of Cartilage Tissue

2020

Polymers, 12 (7), 1598

Tsanaktsidou E., Kammona O., Kiparissides C.

On the Synthesis and Characterization of Biofunctional Hyaluronic Acid Based Injectable Hydrogels for the Repair of Cartilage Lesions

2019

European Polymer Journal, 114, 47-56

Pladis P., Kiparissides C.

110th Anniversary: Nonideal Mixing Phenomena in High-Pressure Low-Density Polyethylene Autoclaves: Prediction of Variable Initiator Efficiency and Ethylene Decomposition

2019

Industrial & Engineering Chemistry Research, 58 (29), 13093-13111

MINOAN – Smart Sustainable
Energy Conversion and Management

GREEN – Geo-Resources, Energy
& Environmental Management

GrEnEA – Green Energy
& Environmental Applications

LIM – Laboratory
of Inorganic Materials

ARTEMIS – Advanced Renewable
Technologies for Energy & Materials
Integrated Systems

NRRE – Natural Resources
& Renewable Energies

PSDI – Laboratory of Process
Systems Design and Implementation

LPRE – Laboratory of Polymer
Reaction Engineering

NICE – Novel materIals
for Clean Energy Applications

LEFH – Laboratory of Environmental
Fuels/Biofuels and Hydrocarbons

HydPro – Hydroprocessing

BCPL – Biological Computation
& Process Laboratory

LEET – Laboratory of Environmental & Energy Transition technologies
(GrEnEA, Green & Minoan Groups)